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Aldolase B antibody

产品编号:S3224

产品描述:Aldolase B antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2890.00

订购:订购

说明书:

Aldolase B antibody

Cat.#: S3224

Rabbit Polyclonal Antibody

Clone ID: polyclonal
Swiss Prot: P05062
Mol Weight: 34.76kDa
Size: 100 µl

Description

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq]

Recommended Applications

WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000

Species Reactivity

Human


Products Data


Sample (30 ug of whole cell lysate)
A: 293T
B: A431
C: JurKat
D: Raji
10% SDS PAGE
diluted at 1:1000
  
  

Specificity

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 84 and 298 of Aldolase B

Storage Buffer & Conditions

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

ALDOB, ALDB, ALDO2