产品编号:S0094

产品描述:AKR1C3 antibody

反应种属:

实验方法:

标记:

规格:100ug

供应商:Epitomics

价格(RMB):2890.00

订购:

说明书:

AKR1C3 antibody

Cat.#: S0094

Rabbit Polyclonal Antibody

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]

Recommended Applications

ICC,WB

Species Reactivity

Human

Products Data

Sample (30 ug of whole cell lysate)
A: Hep G2
10% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using AKR1C3 antibody at 1:100 dilution.

  

Specificity

261 - 323 of Human AKR1C3

Storage Buffer & Conditions

1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS