产品编号:S2715

产品描述:AIF antibody

反应种属:

实验方法:

标记:

规格:100ug

供应商:Epitomics

价格(RMB):2890.00

订购:

说明书:

AIF antibody

Cat.#: S2715

Rabbit Polyclonal Antibody

Description

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq]

Recommended Applications

IHC,WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000
IHC: 1:100-1:250

Species Reactivity

Human

Products Data

Sample (30 ug of whole cell lysate)
A: H1299
B: Hep G2
7.5% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded SW480 Xenograft, using AIF antibody at 1:100 dilution.

  

Specificity

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 78 and 296 of AIF

Storage Buffer & Conditions

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

AIFM1, AIF, MGC111425, PDCD8