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ADH1A/1B/1C antibody

产品编号:2980-1

产品描述:ADH1A/1B/1C antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2500.00

订购:订购

说明书:

ADH1A/1B/1C antibody

Cat.#: 2980-1

Rabbit Monoclonal Antibody

Clone ID: EPR4440
Swiss Prot: P07327
Mol Weight: 40kDa
Size: 100ul

Description

ADH1A/1B/1C are class I alcohol dehydrogenases that consist of alpha, beta, gamma subunits, which are members of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenases, consisting of several homo- and heterodimers of the three subunits, exhibit high activity for ethanol oxidation and play a major role in ethanol catabolism. The alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. ADH1A is monomorphic and predominant in fetal and infant livers, whereas ADH1B and ADH1C are polymorphic and strongly expressed in adult livers.

Recommended Applications

WB, IHC, IP

Applications and Recommended Dilution Factors

WB: 1:1,000-10,000
IHC: 1:100 - 250
IP: 1:10 - 100

Species Reactivity

Human, Mouse, Rat


Products Data


Western blot analysis on (A) fetal liver, (B) rat liver, and (C) mouse liver lysates using anti-ADH1A/1B/1C RabMAb (cat. # 2980-1).

Immunohistochemical staining of paraffin-embedded human liver tissue using anti-ADH1A/1B/1C RabMAb (cat. #2980-1).
  

Specificity

A synthetic peptide corresponding to residues in human ADH1A/1B/1C was used as an immunogen.

Storage Buffer & Conditions

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Description References

1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.