产品编号:S2412

产品描述:Adducin alpha antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2890.00

订购:

说明书:

Adducin alpha antibody

Cat.#: S2412

Rabbit Polyclonal Antibody

Description

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq]

Recommended Applications

WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000

Species Reactivity

Human

Products Data

Sample (30 ug of whole cell lysate)
A: A431
10% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded SG xenograft , using Alpha-adducin antibody at 1:100 dilution.

  

Specificity

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 198 of Human ADD1

Storage Buffer & Conditions

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

ADD1, ADDA, MGC3339, MGC44427