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ADAM15 antibody

产品编号:S0305

产品描述:ADAM15 antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2890.00

订购:订购

说明书:

ADAM15 antibody

Cat.#: S0305

Rabbit Polyclonal Antibody

Clone ID: polyclonal
Swiss Prot: Q13444
Mol Weight: 92.98kDa
Size: 100 µl

Description

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Recommended Applications

WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000

Species Reactivity

Human, Mouse


Products Data


Sample (30 ug of whole cell lysate)

A: Hep G2

7.5% SDS PAGE

diluted at 1:1000

Sample (30 ug of whole cell lysate)

A: NIH-3T3

7.5% SDS PAGE

ADAM15 antibody

diluted at 1:1000
  

Specificity

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 225 of ADAM15

Storage Buffer & Conditions

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

ADAM15, MDC15