产品编号:2648-1
产品描述:Acyl protein thioesterase 1 antibody
反应种属:
实验方法:
标记:
规格:100ul
供应商:Epitomics
价格(RMB):2500.00
订购:
说明书:
Cat.#: 2648-1
Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids (1). APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (2). The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia (1). Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes (3).
WB, ICC, FC
WB: 1:1,000 - 2,000
ICC: 1:500 - 1000
FC: 1:50
Human, Mouse, Rat
A synthetic peptide corresponding to residues in human Acyl protein thioesterase 1 was used as an immunogen.
Store at -20C. 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
LYPLA1, APT1, LPL1, Acyl-protein thioesterase 1, Lysophospholipase 1;Lysophospholipase I
1. Wang A, et al. Biochim Biophys Acta. 1437(2):157-69, 1999 2. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res., 36:D190-D195 (2008) 3. Wang A, et al. Biochim Biophys Acta. 1484(2-3):207-14, 2000
