产品编号:S0740

产品描述:ACVRL1 antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2890.00

订购:

说明书:

ACVRL1 antibody

Cat.#: S0740

Rabbit Polyclonal Antibody

Description

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]

Recommended Applications

WB

Applications and Recommended Dilution Factors

WB: 1:500-1:3000

Species Reactivity

Human, Mouse

Products Data

Sample(30 ug of whole cell lysate)
A:Hep G2
7.5% SDS PAGE
diluted at 1:1000

Sample (30 ug of whole cell lysate)

A:NIH-3T3
7.5% SDS PAGE

diluted at 1:1000

  

Specificity

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 109 and 281 of ACVRL1

Storage Buffer & Conditions

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names

ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I