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ACVRL1 antibody

产品编号:2940-1

产品描述:ACVRL1 antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2100.00

订购:订购

说明书:

ACVRL1 antibody

Cat.#: 2940-1

Rabbit Monoclonal Antibody

Clone ID: EPR4074
Swiss Prot: P37023
Mol Weight: 56kDa
Size: 100ul

Description

ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Recommended Applications

WB

Applications and Recommended Dilution Factors

WB: 1:1,000-10,000

Species Reactivity

Human, Mouse, Rat


Products Data


Western blot analysis on (A) JAR, (B) Daudi, and (C) Jurkat cell lysates using anti-ACVRL1 RabMAb (cat. # 2940-1).
  
  

Specificity

A synthetic peptide corresponding to residues in human ACVRL1 was used as an immunogen.

Storage Buffer & Conditions

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Description References

1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.