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ACVR1B antibody

产品编号:3455-1

产品描述:ACVR1B antibody

反应种属:

实验方法:

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2500.00

订购:订购

说明书:

ACVR1B antibody

Cat.#: 3455-1

Rabbit Monoclonal Antibody

Clone ID: EPR4815
Swiss Prot: P36896
Mol Weight: 52kDa
Size: 100ul

Description

ACVR1B is an activin A type IB receptor. Activins are dimeric growth and differentiation factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases, which include at least two type I and two type II receptors. ACVR1B is a type I receptor that is essential for signaling. Mutations in this protein are associated with pituitary tumors.

Recommended Applications

WB, IHC, ICC, FC

Applications and Recommended Dilution Factors

WB: 1:1,000-10,000
IHC: 1:500-1000
ICC: 1:100-250
FC: 1:100-500

Species Reactivity

Human, Mouse, Rat


Products Data


Western blot analysis on (A) human brain, (B) fetal kidney, (C) SH-SY5Y, (D) U87-MG, and (E) fetal liver lysates using anti-ACVR1B RabMAb (cat. #3455-1).

Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ACVR1B RabMAb (cat. #3455-1).
  

Specificity

A synthetic peptide corresponding to residues in the extracellular domain of human ACVR1B was used as an immunogen.

Storage Buffer & Conditions

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names

ALK4

Description References

1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.