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Recombinant Human gAcrp30/Adipolean Variant

产品编号:A227-25

产品描述:Recombinant Human gAcrp30/Adipolean Variant

反应种属:

实验方法:

标记:

规格:25ug

供应商:Leinco

价格(RMB):5205.00

订购:订购

说明书:

Recombinant Human gAcrp30/Adipolean Variant
(apm-1 variant)
Prod. No.: A227
Source E. Coli
Pkg. Size: 1 mg, 25 µg

Description
Background:

The gAcrp30 variant is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, Acrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. This naturally occurring variant of human gAcrp30/Adipolean is an 18.1 kDa protein, containing 14 amino acids extra at the N-terminus of human gAcrp30/Adipolean.

Source
E. Coli
State of Matter
 
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
The biological activity of Human gAcrp30/Adipolean Variant is determined by a cytotoxicity assay using M1 cells. The expected ED50 for this effect is 0.5-1.0 µg/ml.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
PGAEGPRGFP GIQGRKGEPG EGAYVYRSAF SVGLETYVTI PNMPIRFTKI FYNQQNHYDG STGKFHCNIP GLYYFAYHIT VYMKDVKVSL FKKDKAMLFT YDQYQENNVD QASGSVLLHL EVGDQVWLQV YGEGERNGLY ADNDNDSTFT GFLLYHDTN

Related Products

Anti-Human Adipolean Variant (Antigen Aff. Pur.) (Leinco Prod. No.: A225)