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Recombinant Mouse VEGF R1

产品编号:V122-1

产品描述:Recombinant Mouse VEGF R1

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Mouse Vascular Endothelial Growth Factor Receptor 1 (VEGF R1)
Purified No Carrier Protein
(FLT1, FLT, Vascular Permeability Factor Receptor, Tyrosine-Protein Kinase Receptor FLT, Tyrosine-Protein Kinase FRT, Fms-Like Tyrosine Kinase 1, FRT)
Prod. No.: V122
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C

Description
Background:

Vascular endothelial growth factor receptor 1 (VEGF R1), also known as FLT1, is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis.1 VEGFR1 is mainly expressed in vascular endothelial cells but also in peripheral blood monocytes. VEGFR1 signaling promotes lymphangiogenesis as well as angiogenesis mainly by increasing bone marrow–derived macrophage recruitment.2

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse VEGF R1 is Mr 110 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 150-170 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

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References
1. Sreenivasan et al. (2009) Exp Cell Res. 315: 877
2. Masabumi Shibuya et al. (2008) Arteriosclerosis, Thrombosis, and Vascular Biol. 28: 658
Related Products
Anti-Mouse VEGF R1-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: V159)
Anti-Mouse VEGF R1 (Antigen Aff. Pur.) (Leinco Prod. No.: V136)