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Recombinant Mouse VEGF 120

产品编号:V123-25

产品描述:Recombinant Mouse VEGF 120

反应种属:

实验方法:

标记:

规格:25ug

供应商:Leinco

价格(RMB):12375.00

订购:订购

说明书:

Recombinant Mouse Vascular Endothelial Growth Factor 120 (VEGF 120)
Purified No Carrier Protein
(VEGFA, MGC70609, VPF, VAS, Folliculostellate Cell-Derived Growth Factor, Glioma-Derived Endothelial Cell Mitogen)
Prod. No.: V123
Source E. coli
Pkg. Size: 1 mg, 5 µg, 25 µg
Storage: -20°C to -70°C

Description
Background:

Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine1 is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of endothelial cells and directs them to build new vessels.2 VEGF are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis). Abnormal VEGF function is associated with inflammatory diseases including atherosclerosis, and hyperthyroidism.3,4,5,6\

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse VEGF 120 is Mr 14 kDa (monomer).
State of Matter
Lyophilized
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

aptt egeqkshevi kfmdvyqrsy crpietlvdi fqeypdeiey ifkpscvplm rcagccndea lecvptsesn itmqimrikp hqsqhigems flqhsrcecr pkkdrtkpek cdkprr (Gly117Glu & Glu118Arg)

References
1. Folkman J et al. (2008) FASEB J. 22: 3728
2. Goodsell DS et al. (2002) The Oncologist 7: 569
3. Mugishima H. et al. (2006) J Atheroscler Thromb. 13: 130
4. Claesson-Welsh L et al. (2006) Exp Cell Res. 312: 549
5. Claesson-Welsh L et al. (1999) Trends Biochem Sci. 28: 488
6. Ellis LM et al. (2005) J Clin Oncol. 23: 1011