产品编号:V129-1
产品描述:Recombinant Human VCAM-1
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Human Vascular Cell Adhesion Molecule-1 (VCAM-1)
Purified No Carrier Protein
(CD106, INCAM-100, VLA4)
Prod. No.: V129
Source NSO Cells
Pkg. Size: 1 mg, 50 µg, 200 µg
Storage: -20°C to -70°C
Description
Background:
Vascular cell adhesion molecule 1, also known as VCAM1 is an immunoglobulin-like adhesion molecule expressed on activated endothelial cells.1 This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. VCAM-1 promotes the adhesion of lymphocytes, monocytes, eosinophils, and basophils.
Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Human VCAM-1 is Mr 74 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90-95 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
mfkiett pesrylaqig dsvsltcstt gcespffswr tqidsplngk vtnegttstl tmnpvsfgne hsylctatce srklekgiqv eiysfpkdpe ihlsgpleag kpitvkcsva dvypfdrlei dllkgdhlmk sqefledadr ksletkslev tftpviedig kvlvcraklh idemdsvptv rqavkelqvy ispkntvisv npstklqegg svtmtcsseg lpapeifwsk kldngnlqhl sgnatltlia mrmedsgiyv cegvnligkn rkevelivqe kpftveispg priaaqigds vmltcsvmgc espsfswrtq idsplsgkvr segtnstltl spvsfenehs ylctvtcghk klekgiqvel ysfprdpeie msgglvngss vtvsckvpsv ypldrleiel lkgetileni efledtdmks lenkslemtf iptiedtgka lvcqaklhid dmefepkqrq stqtlyvnva prdttvlvsp ssileegssv nmtclsqgfp apkilwsrql pngelqplse natltlistk medsgvylce ginqagrsrk eveliiqvtp kdikltafps esvkegdtvi isctcgnvpe twiilkkkae tgdtvlksid gaytirkaql kdagvyeces knkvgsqlrs ltldvqgren nkdyfspe
References
1. Yuqing Huo et al. (2001) J Clin Invest 107: 1209
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