产品编号:T402-1
产品描述:Recombinant Human TRAIL R3
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Human TNF-Related Apoptosis-Inducing Ligand Receptor 3 (TRAIL R3)
Purified No Carrier Protein
(TRID, TNFRSF10C, CD263, DCR1, LIT, MGC149501, MGC149502)
Prod. No.: T402
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C
Description
Background:
TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor1 that can inhibit TRAIL-induced apoptosis.2 TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.3
Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Human TRAIL R3 is Mr 48 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 75-90 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
attar qeevpqqtva pqqqrhsfkg eecpagshrs ehtgacnpct egvdytnasn nepscfpctv cksdqkhkss ctmtrdtvcq ckegtfrnen spemcrkcsr cpsgevqvsn ctswddiqcv eefganatve tpaaeetmnt spgtpapaae etmntspgtp apaaeetmtt spgtpapaae etmttspgtp aiegrmdpks cdkthtcppc papellggps vflfppkpkd tlmisrtpev tcvvvdvshe dpevkfnwyv dgvevhnakt kpreeqynst yrvvsvltvl hqdwlngkey kckvsnkalp apiektiska kgqprepqvy tlppsrdelt knqvsltclv kgfypsdiav ewesngqpen nykttppvld sdgsfflysk ltvdksrwqq gnvfscsvmh ealhnhytqk slslspgkhh hhhh
References
1. Fornace AJ Jr. et al. (1999) Oncogene 18: 4153
2. Büchler MW et al. (2001) Anticancer Res. 21: 3153
3. Smith CA et al. (1997) J Exp Med. 186: 1165
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