产品编号:T395-1
产品描述:Recombinant Mouse TNF RI
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Mouse Tumor Necrosis Factor Receptor I (TNF RI)
Purified No Carrier Protein
(TNFRSF1A, P55, TBP1, CD120a, FPF, MGC19588, TNF-R, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55-R, p60)
Prod. No.: T395
Source NSO Cells
Pkg. Size: 1 mg, 50 µg
Storage: -20°C to -70°C
Description
Background:
Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated.1 TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses.2 It regulates immune and inflammatory responses.3
Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse TNF RI is Mr 48.6 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 70 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
l vpslgdrekr dslcpqgkyv hsknnsicct kchkgtylvs dcpspgrdtv crecekgtft asqnylrqcl scktcrkems qveispcqad kdtvcgcken qfqrylseth fqcvdcspcf ngtvtipcke tqntvcncha gfflresecv pcshckknee cmklclpppl anvtnpqdsg tadiegrmdp kscdkthtcp pcpapellgg psvflfppkp kdtlmisrtp evtcvvvdvs hedpevkfnw yvdgvevhna ktkpreeqyn styrvvsvlt vlhqdwlngk eykckvsnka lpapiektis kakgqprepq vytlppsrde ltknqvsltc lvkgfypsdi avewesngqp ennykttppv ldsdgsffly skltvdksrw qqgnvfscsv mhealhnhyt qkslslspgk
References
1. Reza Dana et al. (2000) Arch Ophthalmol. 118: 1666
2. Donner DB et al. (2008) J Immunol. 181: 1288
3. Pasparakis M et al. (2008) Nat Immunol. 9: 1015
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