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Recombinant Human TFF2

产品编号:T229-20

产品描述:Recombinant Human TFF2

反应种属:

实验方法:

标记:

规格:20ug

供应商:Leinco

价格(RMB):5175.00

订购:订购

说明书:

Recombinant Human Recombinant Human Trefoil Factor 2 (TFF2)
(SML1, Spasmolytic Polypeptide (SP))
Prod. No.: T229
Source E. Coli
Pkg. Size: 1 mg, 5 µg, 20 µg

Description
Background:

Trefoil factor 2 (TFF2), also known as spasmolytic protein 1 is a small secreted protein1 and a member of the trefoil family of peptides. It is a highly stable peptide which is abundantly expressed and secreted by mucous cells of the stomach and has a functions in gastric cytoprotection.2 TFF2 is also detected at high concentrations around sites of ulceration. It is protective against mucosal damaging agents and stimulates cell motility.1 TFF2 is also useful in the treatment of colitis.3

Source
E. Coli
State of Matter
 
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
The biological activity of Human Recombinant Human Trefoil Factor 2 is determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence

EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY

References
1. Westley BR et al. (2000) Gut 46: 454
2. Wang TC et al. (2002) Biochemical and biophysical research communications 293: 366
3. Panés J. et al. (2004) J Leukoc Biol. 75: 214