产品中心

产品搜索 抗体高级搜索

首页 > 产品列表 > 细胞因子/重组蛋白/抗原 > 重组与天然蛋白质

Recombinant Mouse SIGIRR

产品编号:S576-1

产品描述:Recombinant Mouse SIGIRR

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Mouse Single Immunoglobulin Domain-Containing IL-1 Receptor-Related Protein (SIGIRR)
Purified No Carrier Protein
(Single Ig IL-1R-related Molecule, MGC110992, TIR8)
Prod. No.: S576
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C

Description
Background:

Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family.1 It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling.2 It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.3

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse SIGIRR is Mr 39 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 63 kDa.
State of Matter
Lyophilized
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<0.1 ng per 1 µg as determined by the LAL method
Amino Acid Sequence

magvcdmapn flspsedqal glalgreval nctawvfsrp qcpqpsvqwl kdglalgngs hfslhedfwv sanfseivss vlvlnltnae dygtftcsvw nvsshsftlw ragpaghksc dkthtcppcp apellggpsv flfppkpkdt lmisrtpevt cvvvdvshed pevkfnwyvd gvevhnaktk preeqynsty rvvsvltvlh qdwlngkeyk ckvsnkalpa piektiskak gqprepqvyt lppsrdeltk nqvsltclvk gfypsdiave wesngqpenn ykttppvlds dgsfflyskl tvdksrwqqg nvfscsvmhe alhnhytqks lslspgk

References
1. Mantovani A.et al. (2003) Eur Cytokine Netw. 14: 211
2. Li xet al. (2005) J Biol chem. 280: 25233
3. Li X et al. (2007) Immunity 26: 461
Related Products
Anti-Mouse SIGIRR (CT) (Leinco Prod. No.: S556)
SIGIRR (CT) Blocking Peptide (Leinco Prod. No.: S559)
Anti-Human SIGIRR-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: S578)
Anti-Human SIGIRR (Antigen Aff. Pur.) (Leinco Prod. No.: S580)
Recombinant Human SIGIRR (Leinco Prod. No.: S575)