产品编号:S502-10
产品描述:Recombinant Mouse SDF-1β
反应种属:
实验方法:
标记:
规格:10ug
供应商:Leinco
价格(RMB):4200.00
订购:
说明书:
Recombinant Mouse Stromal Cell-Derived Factor-1 Beta (SDF-1β)
Purified No Carrier Protein
(Thymic Lymphoma Cell Stimulating Factor-Beta (TLSF-b), CXCL12b, Pre-B Cell Growth-Stimulating Factor (PBSF))
Prod. No.: S502
Source E. coli
Pkg. Size: 1 mg, 2 µg, 10 µg, 100 µg
Description
Background:
SDF-1 beta (stromal cell-derived factor-1 beta) is a non-glycosylated Polypeptide that is produced in E-Coli, belonging to the alpha chemokine (C-X-C) family of cytokines.1 SDF-1beta is a highly efficacious chemoattractant for resting lymphocytes and CD34(+) progenitor cells, and it efficiently blocks the CXCR-4-mediated entry into cells of T cell line tropic strains of HIV type 1 (HIV-1). SDF-1beta promotes HIV-1 replication and disease progression.2
Source
E. coli
Molecular Weight
The molecular weight of Recombinant Mouse SDF-1β is Mr 8.526 kDa.
State of Matter
Lyophilized
Purity
>97% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
The biological activity of Mouse Stromal Cell-Derived Factor-1 Beta is determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM
References
1. Muller HW et al. (2000) Eur J Neurosci. 12: 1857
2. Nagai Y et al. (1998) Proceedings of National Acad Sci USA 95: 6331
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