产品编号:R134-1mg
产品描述:Recombinant Cotton Rat RANTES
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Rat Regulation Upon Activation Normal T Cell Express Sequence (RANTES)
(CCL5, D17S136E, MGC17164, SCYA5, SIS-Delta, TCP228)
Prod. No.: R134
Source E. Coli
Pkg. Size: 1 mg, 5 µg, 25 µg, 100 µg
Description
Background:
RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine1 is an important mediators of the immune and inflammatory response.2 It is also a potent chemoattractant for T cells 3 and eosinophils.4 RANTES is involved in many inflammatory diseases, for example, bronchial asthma, delayed-type hypersensitivity reactions, viral infections, arthritis, chronic eosinophilic pneumonia, and idiopathic interstitial pneumonia.5
Source
E. Coli
State of Matter
Purity
>98% by SDS Page
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
The biological activity of Rat Regulation Upon Activation Normal T Cell Express Sequence is determined by its ability to chemoattract rat peritoneal macrophages using a concentration range of 50.0-100.0 ng/ml.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
References
1. Lee SC et al. (2004) J Neurochem. 90: 297
2. Borkowski J et al. (2004) Arch Immunol Ther Exp (Warsz) 52: 201
3. Geiger H et al. (2005) Kidney Blood Press Res 28: 48
4. Hirata I. et al. (2008) Dig Dis Sci.
5. Emilie D et al. (1994) J Exp Med. 179: 1689
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