产品编号:P136-1
产品描述:Recombinant Human Persephin(PSP)
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Human Persephin (PSP)
Purified No Carrier Protein
(PSPN)
Prod. No.: P136
Source E. coli
Pkg. Size: 1 mg, 5 µg, 20 µg
Storage: -20°C to -70°C
Description
Background:
Persephin (PSP) is a secreted protein belonging to the glial cell line-derived neurotrophic factor (GDNF) family of the TGF-b superfamily. Just like factor GDNF and neurturin (NTN), PSP promotes the survival of ventral midbrain dopaminergic neurons and prevents their degeneration. Persephin also supports the survival of motor neurons.1 Persephin is expressed at very low levels in most tissues. It is synthesized throughout the nervous system and has both astroglial and neuronal origin.2
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Human PSP is Mr 10.3 kDa.
State of Matter
Lyophilized
Purity
>95% by SDS Page and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
References
1. Johnson EM et al. (1998) Neuron 20: 245
2. Krieglstein K. et al. (1998) J Neurosci Res. 53: 494
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