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Recombinant Human PK2

产品编号:P171-1

产品描述:Recombinant Human PK2

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Human Prokineticin-2 (PK2)
(PROK2, Protein Bv8 homolog)
Prod. No.: P171
Source E. Coli
Pkg. Size: 1 mg, 20 µg

Description
Background:

Prokineticin 2 (PK2) is a cysteine-rich secreted protein1 that is expressed in the testis and in lower levels of the small intestine. PK2 regulates various biological functions including gastrointestinal motility, angiogenesis, circadiam rhythms, and neurogenesis of olfactory bulb.2 It is closely related to EG-VEGF (Prokineticin-1) and binds to two orphan B-protein-coupled receptors termed PK-R1 and PK-R2. PK2 plays roles in both circadian and homeostatic regulation of sleep. PK2 may also be involved in maintaining the awake state in the presence of behavioral challenges.3

Source
E. Coli
State of Matter
 
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
Data not yet available.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence

AVITGACDKD SQCGGGMCCA VSIWVKSIRI CTPMGKLGDS CHPLTRKVPF FGRRMHHTC PCLPGLACLR TSFNRFICLA QK

References
1. Zhou QY et al. (2002) Nature 417: 405
2. Zhou QY et al. (2007) J Biol Chem. 282: 6917
3. Zhou QY et al. (2007) Sleep 30: 247