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Recombinant Human Octreotide(OCT)

产品编号:O119-25

产品描述:Recombinant Human Octreotide(OCT)

反应种属:

实验方法:

标记:

规格:25mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Human Octreotide (OCT)
(Sandostatin)
Prod. No.: O119
Source Synthetic
Pkg. Size: 25 mg, 1 mg, 5 mg
Storage: -20°C

Description
Background:

Octreotide is a potent inhibitor of growth hormone, glucagon, and insulin. It also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone. Octreotide is a good alternative in palliative treatment of symptomatic liver metastases in patients with end-stage malignant disease.1 Octreotide can can also inhibit human colonic cancer cell growth through inhibition of Wnt/beta-catenin signaling pathway.2

Source
Synthetic
State of Matter
 
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<0.125 EU/µg
Amino Acid Sequence

Synthetic Human Octreotide is a single, non-glycosylated, polypeptide chain containing 8 amino acids, having a molecular mass of 1019.26 Dalton and a molecular formula of C49H66N10O10S2.

References
1. Kouloulias VE et al. (2003) Palliat Med. 17: 257
2. Long JW et al. (2009) Pharmazie 64: 126