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Recombinant Human Nanog

产品编号:N140-20

产品描述:Recombinant Human Nanog

反应种属:

实验方法:

标记:

规格:20ug

供应商:Leinco

价格(RMB):5205.00

订购:订购

说明书:

Recombinant Human Nanog
Purified No Carrier Protein
Prod. No.: N140
Source E. coli
Pkg. Size: 1 mg, 20 µg
Storage: -20°C - -70°C

Description
Background:

Nanog, a homeobox transcription factor1, plays a key role in maintaining stem cell pluripotency by regulating the expression of genes critical to stem cell renewal and differentiation.2 In other words, these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm). Nanog may be useful in the immunohistochemical diagnosis of tumors. It is expressed in germ cells of the fetus and in some germ cell tumors of the gonads3 and central nervous system.4

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Human Nanog is Mr 34.7 kDa.
State of Matter
Lyophilized
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<0.1 EU/µg as determined by the LAL method
Amino Acid Sequence

SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDV

References
1. Schöler HR.et al. (2003) Cell 113: 551
2. Pei D. et al. (2005) J Biol. Chem. 280: 1401
3. Rajpert-De Meyts E. et al. (2005) Histopathology 47: 48
4. Ligon KL. et al. (2006) Am J Surg Pathol. 30: 1613
Related Products
Anti-Human Nanog (Antigen Aff. Pur.) (Leinco Prod. No.: N143)
Anti-Human Nanog-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: N144)