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Recombinant Human NOV

产品编号:N141-5

产品描述:Recombinant Human NOV

反应种属:

实验方法:

标记:

规格:5ug

供应商:Leinco

价格(RMB):3315.00

订购:订购

说明书:

Recombinant Human Nephroblastoma Overexpressed Gene (NOV)
Purified No Carrier Protein
(CCN3, IGFBP9, NovH)
Prod. No.: N141
Source E. coli
Pkg. Size: 1 mg, 5 µg, 20 µg
Storage: -20°C to -70°C

Description
Background:

Nephroblastoma overexpressed gene, also known as NOV is a member of the CCN (connective tissue growth factor [CTGF]) family of proteins. These proteins are cysteine-rich and are noted for having growth-regulatory functions.1 NOV is highly expressed in the nervous system.2 NOV is a specific cell fate regulator in the myogenic lineage, acting negatively on key myogenic genes thus controlling the transition from progenitor cells to myoblasts.3 NOV also supports endothelial cell adhesion and angiogenesis through interactions with integrins.4

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Human NOV is Mr 37.1 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55 kDa.
State of Matter
Lyophilized
Purity
>95% by SDS Page and HPLC
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin

<0.1 EU/µg as determined by the LAL method

References
1. Maki RA. et al. (1999) Gene 238: 471
2. Kleinman HK. et al. (2003) FASEB J. 17: 1919
3. Dubois C. et al. (2006) Exp Cell Resp. 312: 1876
4. Martinerie C. et al. (2005) Cell Commun Adhes. 12: 41
Related Products
Human NOV ELISA Development Kit (Leinco Prod. No.: N214)