产品编号:M165-1
产品描述:Recombinant Rat MIP-1α
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Rat Macrophage Inflammatory Protein 1 Alpha (MIP-1α)
Purified No Carrier Protein
(G0S19-1, LD78Alpha, MIP1A, SCYA3, CCL3)
Prod. No.: M165
Source E. coli
Pkg. Size: 1 mg, 5 µg, 20 µg, 100 µg
Storage: -20°C
Description
Background:
Macrophage inflammatory protein 1 alpha (MIP-1 alpha) is a potent inhibitor of hemopoietic stem cell proliferation and is a member of a family of pro- inflammatory mediators, the chemokine family.1 MIP-1 alpha is a particularly interesting chemokine, because in addition to its proinflammatory activities, it inhibits the proliferation of hematopoietic stem cells.2 The role of MIP-1 alpha seems to be related to production of TNF-alpha, which in turn up-regulates vascular adhesion molecules required for neutrophil influx.3
Source
E. coli
Molecular Weight
Recombinant Rat MIP-1a is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7853 Dalson.
State of Matter
Lyophilized
Purity
>95% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
References
1. IB Pragnell et al. (1994) J. Biol. Chem. 269: 4974
2. DN Cook et al. (1996) J. of Leukocyte Biol. 59: 61
3. PA Ward et al. (1995) J of Immunol. 154: 4793
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