产品编号:I-418-1
产品描述:Recombinant Mouse IL-31
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Mouse Interleukin-31 (IL-31)
Prod. No.: I-418
Source E. coli
Pkg. Size: 1 mg, 10 µg
Storage: -20°C
Description
Background:
Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse IL-31 is Mr 15.8 kDa.
State of Matter
Lyophilized
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<0.1 EU/µg as determined by the LAL method
Biological Activity
Data not yet available.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
References
1. Stacey R Dillon et al.(2004) Nature Immunol. 5: 752
2. Homey B. et al.(2006) J Allergy Clin Immunol. 117: 411
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