产品编号:I-417-1
产品描述:Recombinant Human IL-31
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Human Interleukin-31 (IL-31)
Purified No Carrier Protein
Prod. No.: I-417
Source E. coli
Pkg. Size: 1 mg, 10 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Human IL-31 is Mr 15.8 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) and dithiothreitol (DTT) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
shtlpvr llrpsddvqk iveelqslsk mllkdveeek gvlvsqnytl pclspdaqpp nnihspaira ylktirqldn ksvideiieh ldklifqdap etnisvptdt heckrfilti sqqfsecmdl alksltsgaq qatt
References
1. Stacey R Dillon et al.(2004) Nature Immunol. 5: 752
2. Homey B. et al.(2006) J Allergy Clin Immunol. 117: 411
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