产品编号:I-526-1
产品描述:Recombinant Mouse IL-20
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Mouse Interleukin-20 (IL-20)
Purified No Carrier Protein
(ZCYTO10, IL10D)
Prod. No.: I-526
Source E. coli
Pkg. Size: 1 mg, 25 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin-20 (IL-20) is a pleiotropic inflammatory protein belonging to the IL-10 family of cytokines. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.1 IL-20 plays a critical role in the induction and maintenance of psoriasis.2
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse IL-20 is Mr 17 kDa.
State of Matter
Lyophilized
Purity
>97% by SDS Page and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
References
1. Kupper T.Set al. (2006) Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chem. 5: 243
2. Dam TM. et al. (2009) Br J Dermatol. 160: 284
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