产品编号:I-812-1
产品描述:Recombinant Rat IL-17
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Rat Interleukin-17 (IL-17)
Purified No Carrier Protein
(CTLA8, IL17A)
Prod. No.: I-812
Source E. coli
Pkg. Size: 1 mg, 25 µg, 100 µg
Storage: -20°C
Description
Background:
Interleukin 17 (IL-17) is a T cell cytokine that induces monocyte migration and inflammation.1 IL-17-producing cell could serve as a potential prognostic marker and a novel therapeutic target for hepatocellular carcinoma (HCC).2 IL-17 may be important in recruiting monocytes into the joints of patients with RA, supporting IL-17 as a therapeutic target in RA.1
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Rat IL-17A is Mr 30.0 kDa.
State of Matter
Lyophilized
Formulation
The protein was 0.2 µm filtered and lyopohilized from 10 mM NaCitrate, pH 3.0
Purity
<95% by SDS Page
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Biological Activity
Recombinant Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured rat fibroblasts.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS
References
1. Pope RM et al. (2009) J Immunol. 182: 3884
2. Zheng L et al. (2009) J Hepatol.
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