产品编号:I-534-1
产品描述:Recombinant Human IL-5
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Rat Interleukin-5 (IL-5)
Purified No Carrier Protein
(EDF, BCDFII, TRF)
Prod. No.: I-534
Source Sf 21 Insect Cells
Pkg. Size: 1 mg, 10 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils.1 IL-5 is a TH2 cytokine which is part of the hematopoietic family. Unlike other members of this cytokine family in its active form, this glycoprotein is a homodimer.2 IL-5 expression is regulated by several transcription factors including GATA-3.3
Source
Sf 21 Insect Cells
Molecular Weight
The predicted molecular weight of Recombinant Human IL-5 is Mr 13 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 14 and 17 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
meipmstvvk etliqlsthr alltsnetmr lpvpthknhq lcigeifqgl dilknqtvrg gtveilfqnl slikkyidgq kekcgeerrk trhfldylqe flgvmstewa mev
References
1. Capron M. et al. (1994) J Exp Med 179: 703
2. Graber P et al. (1993) Nature 363: 172
3. Inokuma S et al. (2005) Int Arch Allergy Immunol 1: 55
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