产品编号:I-532-1
产品描述:Recombinant Mouse IL-5
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Mouse Interleukin-5 (IL-5)
Purified No Carrier Protein
(EDF, BCDFII, TRF)
Prod. No.: I-532
Source Sf 21 Insect Cells
Pkg. Size: 1 mg, 5 µg, 25 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils.1 IL-5 is a TH2 cytokine which is part of the hematopoietic family. Unlike other members of this cytokine family in its active form, this glycoprotein is a homodimer.2 IL-5 expression is regulated by several transcription factors including GATA-3.3
Source
Sf 21 Insect Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse IL-5 is Mr 13.1 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 15-18 kDa.
State of Matter
Solution
Formulation
This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing, in the presence of a carrier protein, this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage, aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
meipmstvvk etltqlsahr alltsnetmr lpvpthknhq lcigeifqgl dilknqtvrg gtvemlfqnl slikkyidrq kekcgeerrr trqfldylqe flgvmstewa meg
References
1. Capron M. et al. (1994) J Exp Med 179: 703
2. Graber P et al. (1993) Nature 363: 172
3. Inokuma S et al. (2005) Int Arch Allergy Immunol 1: 55
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