产品编号:I-221-1
产品描述:Recombinant Rat IL-4
反应种属:
实验方法:
标记:
规格:1mg
供应商:Leinco
价格(RMB):面议
订购:
说明书:
Recombinant Rat Interleukin-4 (IL-4)
Purified No Carrier Protein
(BCGF, BCDF, B Cell Stimulating Factor, BSF-1)
Prod. No.: I-221
Source E. coli
Pkg. Size: 1 mg, 5 µg, 25 µg
Storage: -20°C to -70°C
Description
Background:
Interleukin-4 (IL-4) is a pleiotropic immune cytokine secreted by activated TH2 cells that inhibits bone resorption.1 IL-4 is critical for inducing allergic responses.2 It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is also a key regulator in humoral and adaptive immunity. IL-4 is required for the pathogenesis of atopic diseases and immune regulation.3
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Rat IL-4 is Mr 13.5 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
cndsplreii ntlnqvtekg tpctemfvpd vltatrntte nelicrasrv lrkfyfprdv ppclknksgv lgelrklcrg vsglnslrsc tvnestlttl kdfleslksi lrgkylqsct sms
References
1. J Wesley Pike et al. (2001) PNAS 98: 2443
2. Fred D. Finkelman et al. (2003) J Immunol. 170: 3835
3. Kaplan MH et al. (2008) J Immunol. 180: 3551
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