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Recombinant Rat IL-1 Rrp2

产品编号:I-570-1

产品描述:Recombinant Rat IL-1 Rrp2

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Rat Interleukin-1 Receptor Related Protein 2 (IL-1 Rrp2)
Purified No Carrier Protein
(IL-1 R6)
Prod. No.: I-570
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C

Description
Background:

Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP.1 IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA).2

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Rat IL-1 Rrp2 is Mr 63 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

gnctdvymh hemisegqpf pfnctyppvt ngavnltwhr tpskspisin rhvrihqdqs wilflplale dsgiyqcvik dahscyriai nltvfrkhwc dssneessin ssdeyqqwlp igksgsltch lyfpescvld sikwykgcee ikvskkfcpt gtkllvnnid vedsgsyacs arlthlgrif tvrnyiavnt kevgsggrip nitypknnsi evqlgstliv dcnitdtken tnlrcwrvnn tlvddyyndf kriqegietn lslrnhilyt vnitflevkm edyghpftch aavsaayiil krpapdfray diegrmdpks cdkthtcppc papellggps vflfppkpkd tlmisrtpev tcvvvdvshe dpevkfnwyv dgvevhnakt kpreeqynst yrvvsvltvl hqdwlngkey kckvsnkalp apiektiska kgqprepqvy tlppsrdelt knqvsltclv kgfypsdiav ewesngqpen nykttppvld sdgsfflysk ltvdksrwqq gnvfscsvmh ealhnhytqk sls

References
1. Sims JE et al. (2004) J Biol Chem. 279: 13677
2. Taylor JJ et al. (2007) Clin Exp Immunol. 147: 217
Related Products
Recombinant Human IL-1 Rrp2 (Leinco Prod. No.: I-593)
Anti-Rat IL-1 Rrp2 (Leinco Prod. No.: I-680)
Anti-Human IL-1 Rrp2 (Leinco Prod. No.: I-714)