产品搜索 抗体高级搜索

首页 > 产品列表 > 细胞因子/重组蛋白/抗原 > 重组与天然蛋白质

Recombinant Human HGF (NSO Cell Expressed)

产品编号:H1475-25

产品描述:Recombinant Human HGF (NSO Cell Expressed)

反应种属:

实验方法:

标记:

规格:25ug

供应商:Leinco

价格(RMB):16350.00

订购:订购

说明书:

Recombinant Human Hepatocyte Growth Factor (HGF)
Purified No Carrier Protein
(Scatter Factor [SF], Hepatopoietin A [HPTA], F-TCF, HGFB, DFNB39)
Prod. No.: H1475
Source NSO Cells
Pkg. Size: 1 mg, 5 µg, 25 µg
Storage: -20°C to -70°C

Description
Background:

Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells. It has been shown to have a major role in embryonic organ development, in adult organ regeneration and in wound healing.1

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.

Source
NSO Cells
Molecular Weight
This protein consists of a disulfide-linked heterodimer. The predicted molecular mass is 53.7 kDa (α chain) and 26 kDa (β chain). The actual molecular weight of Recombinant Human HGF is Mr 70-80 kDa under nonreducing conditions; and 60-65 kDa and 30-40 kDa under reducing conditions.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

qrkrrntih efkksakttl ikidpalkik tkkvntadqc anrctrnkgl pftckafvfd karkqclwfp fnsmssgvkk efghefdlye nkdyirncii gkgrsykgtv sitksgikcq pwssmipheh sflpssyrgk dlqenycrnp rgeeggpwcf tsnpevryev cdipqcseve cmtcngesyr glmdhtesgk icqrwdhqtp hrhkflpery pdkgfddnyc rnpdgqprpw cytldphtrw eycaiktcad ntmndtdvpl etteciqgqg egyrgtvnti wngipcqrwd sqyphehdmt penfkckdlr enycrnpdgs espwcfttdp nirvgycsqi pncdmshgqd cyrgngknym gnlsqtrsgl tcsmwdknme dlhrhifwep dasklnenyc rnpdddahgp wcytgnplip wdycpisrce gdttptivnl dhpviscakt kqlrvvngip trtnigwmvs lryrnkhicg gslikeswvl tarqcfpsrd lkdyeawlgi hdvhgrgdek ckqvlnvsql vygpegsdlv lmklarpavl ddfvstidlp nygctipekt scsvygwgyt glinydgllr vahlyimgne kcsqhhrgkv tlneseicag aekigsgpce gdyggplvce qhkmrmvlgv ivpgrgcaip nrpgifvrva yyakwihkii ltykvpqs

References
1. Lyon M. et al. (2000) Proteoglycans: structure, biology and molecular interactions.: 27
Related Products
Recombinant Human HGF (Leinco Prod. No.: H255)
Anti-Human HGF-Biotin (Antigen Aff. Pur.) (
Leinco Prod. No.: H1479)
Anti-Human HGF (
Leinco Prod. No.: H1480)
Anti-Human HGF (
Leinco Prod. No.: H1484)