产品编号:G596-25
产品描述:Recombinant Rat GM-CSF
反应种属:
实验方法:
标记:
规格:25ug
供应商:Leinco
价格(RMB):12375.00
订购:
说明书:
Recombinant Rat Granulocyte/Macrophage Colony Stimulating Factor (GM-CSF)
Purified No Carrier Protein
(CSF-2, MGI-1GM, Pluripoietin-Alpha)
Prod. No.: G596
Source E. coli
Pkg. Size: 1 mg, 5 µg, 25 µg
Storage: -20°C to -70°C
Description
Background:
Granulocyte-macrophage colony-stimulating factor, often abbreviated to GM-CSF is a pleiotropic cytokine that controls the production and function of blood cells.1 GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes.
GM-CSF has a critical role in regulation of surfactant homeostasis and alveolar macrophage innate immune functions in the lung.2
Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Rat GM-CSF is Mr 14.7 kDa.
State of Matter
Solution
Formulation
This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing, in the presence of a carrier protein, this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage, aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
aptrspnpvt rpwkhvdaik ealsllndmr aleneknedv diisnefsiq rptcvqtrlk lykqglrgnl tklngaltmi ashyqtncpp tpetdceiev ttfedfiknl kgflfdipfd cwkpvqk
References
1. Micheal W. Parker et al. (2008) Cell 134: 496
2. Whitsett et al. (2002) Annual Review of Physiology 64: 775
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