产品编号:G646-100
产品描述:Recombinant Mouse GFRα-2
反应种属:
实验方法:
标记:
规格:100ug
供应商:Leinco
价格(RMB):4875.00
说明书:
Recombinant Mouse Glial Cell-Line Derived Neurotrophic Factor Receptor Alpha-2 (GFRα-2)
Purified No Carrier Protein
(GDNFRB, NRTNR-Alpha, NTNRA, RETL2, TRNR2)
Prod. No.: G646
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C
Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons.1 GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR).2 GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion.3
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