产品中心

产品搜索 抗体高级搜索

首页 > 产品列表 > 细胞因子/重组蛋白/抗原 > 重组与天然蛋白质

Recombinant Rat GDNF Rα1

产品编号:G648-1

产品描述:Recombinant Rat GDNF Rα1

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Rat Glial Cell-Line Derived Neurotrophic Factor Receptor Alpha-1 (GDNF Rα1)
Purified No Carrier Protein
(GFRA1, GDNFR, GDNFRA, GFR-Alpha-1, MGC23045, RET1L, RETL1, TRNR1)
Prod. No.: G648
Source Rat
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C

Description
Background:

Glial Cell-Line Derived Neurotrophic Factor Receptor Alpha 1 (GDNFR-alpha 1), also known as GFRA1, is a novel glycosylphosphatidylinositol-linked cell surface receptor for glial cell line-derived neurotrophic factor (GDNF)1 that is expressed by Spermatogonial stem cells (SSCs).2 GDNF has been known for many years to protect and restore dopamine neurons of the substantia nigra (SN) in lesion models of parkinsonism.3

Source
Rat
Molecular Weight
The predicted molecular weight of Recombinant Rat GDNF Rα1 is Mr 74 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 95 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

drldcv kasdqclkeq scstkyrtlr qcvagketnf sltsgleakd ecrsamealk qkslyncrck rgmkkekncl riywsmyqsl qgndlledsp yepvnsrlsd ifravpfisd vfqqvehisk gnncldaaka cnlddtckky rsayitpctt smsnevcnrr kchkalrqff dkvpakhsyg mlfcscrdia cterrrqtiv pvcsyeerer pnclslqdsc ktnyicrsrl adfftncqpe srsvsnclke nyadcllays gligtvmtpn yvdssslsva pwcdcsnsgn dledclkfln ffkdntclkn aiqafgngsd vtmwqpappv qtttatttta frvknkplgp agseneipth vlppcanlqa qklksnvsgs thlclsdsdf gkdglagass hittksmaap pscslcsieg rmdpkscdkt htcppcpape llggpsvflf ppkpkdtlmi srtpevtcvv vdvshedpev kfnwyvdgve vhnaktkpre eqynstyrvv svltvlhqdw lngkeykckv snkalpapie ktiskakgqp repqvytlpp srdeltknqv sltclvkgfy psdiavewes ngqpennykt tppvldsdgs fflyskltvd ksrwqqgnvf scsvmhealh nhytqkslsl spgkhhhhhh

References
1. Fox GM et al. (1996) Cell 85: 1113
2. Stefan Schlatt et al. (2005) Biol Rep. 73: 1011
3. Burke RE et al. (2006) J Neural Transmission 70: 41