产品中心

产品搜索 抗体高级搜索

首页 > 产品列表 > 细胞因子/重组蛋白/抗原 > 重组与天然蛋白质

Recombinant Human GDF-15

产品编号:G640-1

产品描述:Recombinant Human GDF-15

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Human Growth Differentiation Factor 15 (GDF-15)
Purified No Carrier Protein
(Macrophage Inhibitory Cytokine-1, MIC-1, Placental TGFβ, Prostate Differentiation Factor, PDF, GDF-15, NAG-1, PLAB, PTGFB)
Prod. No.: G640
Source CHO
Pkg. Size: 1 mg, 25 µg
Storage: -20°C to -70°C 

Description
Background:

Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.1 GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.2 GDF15 is predominantly expressed in the liver, with lower levels seen in some other tissues. Its expression in the liver is significantly up-regulated during injury of organs such as liver, kidney, heart and lung.1,2,3 GDF-15 is a promising new biomarker in idiopathic pulmonary arterial hypertension.4

Source
CHO
Molecular Weight
The predicted molecular weight of Recombinant Human MIC-1 is Mr 13 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 14 kDa.
State of Matter
Lyophilized
Purity
>97% by SDS Page and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

arngdhcplg pgrccrlhtv rasledlgwa dwvlsprevq vtmcigacps qfraanmhaq iktslhrlkp dtvpapccvp asynpmvliq ktdtgvslqt yddllakdch cihhhhhh

References
1. Koniaris Let al. (2005)Shock 23: 543
2. Lee S et al. (2000)Mol Cell Biol 20: 3742
3. Sadoshima J et al. (2006)Circ Res 98 : 294
4. Wollert KC. et al. (2008)Am J Respir Crit Cre Med. 178 : 534
Related Products
Anti-Human GDF-15 (Antigen Aff. Pur.) (Leinco Prod. No.: G667)