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Recombinant Mouse GDF-5

产品编号:G654-1

产品描述:Recombinant Mouse GDF-5

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:订购

说明书:

Recombinant Mouse Growth Differentiation Factor-5 (GDF-5)
Purified No Carrier Protein
(CDMP1, LAP4, SYNS2)
Prod. No.: G654
Source E. coli
Pkg. Size: 1 mg, 50 µg
Storage: -20°C to -70°C

Description
Background:

Growth differentiation factor 5 (cartilage-derived morphogenetic protein-1), also known as GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF5 is expressed in the developing central nervous system.1 It increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinsons disease.2 

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse GDF-5 is Mr 13.7 kDa (monomer).
State of Matter
Solution
Formulation
This recombinant protein was 0.2 µm filtered and is supplied in a solution of 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing, in the presence of a carrier protein, this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage, aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

maplan rqgkrpsknl karcsrkalh vnfkdmgwdd wiiapleyea fhceglcefp lrshleptnh aviqtlmnsm dpestpptcc vptrlspisi lfidsannvv ykqyedmvve scgcr

References
1. Sullivan A et al. (2004) J Neurocytol 33: 479
2. OKeeffe G et al. (2005) J Anat 207: 219
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