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Recombinant Human FGF R1β(IIIc)

产品编号:F1043-50

产品描述:Recombinant Human FGF R1β(IIIc)

反应种属:

实验方法:

标记:

规格:50ug

供应商:Leinco

价格(RMB):4725.00

订购:订购

说明书:

Recombinant Human Fibroblast Growth Factor Receptor 1 Beta (FGF R1β (IIIc))
Purified No Carrier Protein
(CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR, N-SAM, FLJ99988, FGFR1)
Prod. No.: F1043
Source NSO Cells
Pkg. Size: 1 mg, 50 µg
Storage: -20°C to -70°C

Description
Background:

Fibroblast growth factor receptor-1 beta (FGFR1- beta) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-beta is expressed in basal epithelial cells and smooth muscle cells.1 FGF R1β supports progression and chemoresistance in subsets of acute myeloid leukemias (AML).2

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Human FGF R1β (IIIc) is Mr 56 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 90-95 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence

rpsptlpeq dalpsseddd ddddssseek etdntkpnpv apywtspekm ekklhavpaa ktvkfkcpss gtpnptlrwl kngkefkpdh riggykvrya twsiimdsvv psdkgnytci veneygsinh tyqldvvers phrpilqagl panktvalgs nvefmckvys dpqphiqwlk hievngskig pdnlpyvqil ktagvnttdk emevlhlrnv sfedageytc lagnsiglsh hsawltvlea leerpavmts plyleiegrd mdpkscdkth tcppcpapel lggpsvflfp pkpkdtlmis rtpevtcvvv dvshedpevk fnwyvdgvev hnaktkpree qynstyrvvs vltvlhqdwl ngkeykckvs nkalpapiek tiskakgqpr epqvytlpps rdeltknqvs ltclvkgfyp sdiavewesn gqpennyktt ppvldsdgsf flyskltvdk srwqqgnvfs csvmhealhn hytqkslsls pgk

References
1. Moscatelli D et al. (2007) Prostate 67: 115
2. Raffi S et al. (2006) Leukemia 20: 979