产品编号:F1041-50
产品描述:Recombinant Human FGF R1α(IIIb)
反应种属:
实验方法:
标记:
规格:50ug
供应商:Leinco
价格(RMB):4725.00
说明书:
Recombinant Human Fibroblast Growth Factor Receptor 1 Alpha (FGF R1α (IIIb))
Purified No Carrier Protein
(CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR, N-SAM, FLJ99988, FGFR1)
Prod. No.: F1041
Source NSO Cells
Pkg. Size: 1 mg, 50 µg
Storage: -20°C to -70°C
Fibroblast growth factor receptor-1 alpha (FGFR1-alpha) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-alpha is expressed in prostate luminal epithelial cells.1 FGFR1alpha signals are posteriorizing factors that control node regression and posterior embryonic development.2
FGFR1-alpha is a splice variant of FGFR1 containing the first immunoglobulin-like domain, whereas FGFR1-beta lacks this domain.2 The presence or absence of this N-terminal domain influences the affinity of the receptor towards aFGF and heparin.3
FGFR1-alpha is expressed in prostate luminal epithelial cells, whereas FGFR1-beta is expressed in basal epithelial cells and smooth muscle cells.
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