产品编号:E112-25

产品描述:Recombinant Human Eotaxin-2

反应种属:

实验方法:

标记:

规格:25µg

供应商:Leinco

价格(RMB):5325.00

订购:

说明书:

Recombinant Human Eotaxin-2
Purified No Carrier Protein
（CCL24, MPIF-2, CkB-6, SCYA24）
Prod. No.: E112
Source E. coli
Pkg. Size: 1 mg, 25 µg
Storage: -20°C to -70°C Detailed storage instructions below.

Description
Background:
Eotaxin-2 is a CC chemokine that is a specific agonist for the chemokine receptor CCR3. It is produced by activated monocytes ａnd T lymphocytes. Eotaxin-2 induces chemotaxis of eosinophils as well as basophils ａnd the release of histamine ａnd leukotriene C4 from basophils. Eotaxin-2 has the same efficacy as eotaxin, but is somewhat less potent. 1
Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells.

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Human Eotaxin-2 is Mr 10.6 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile （CH3CN） ａnd 0.1% trifluoroacetic acid （TFA）.
Purity
>97% by SDS-PAGE ａnd analyzed by silver stain.
Storage ａnd Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human Eotaxin-2 was determined by its ability to chemoattract hCCR-3 transfected rat myeloid Y3 cells ａnd mCCR-3 transfected BaF/3 cells. The expected ED50 for this effect is typically 0.01 - 0.05 μg/ml for both assays.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
vvip spccmffvsk ripenrvvsy qlssrstclk ggvifttkkg qqfcgdpkqe wvqrymknld akqkkaspra ravavkgpvq rypgnqttc

Country of Origin
USA
References
1. Marco Baggiolini et al. （1997） J. Exp. Med. 185: 2171
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