产品编号:E226-1

产品描述:Recombinant Rat E-Selectin

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:

说明书:

Recombinant Rat E-Selectin
Purified No Carrier Protein
（SELE, CD62E, Endothelial Leukocyte Adhesion Molecule （ELAM）, ELAM1, ESEL, LECAM2）
Prod. No.: E226
Source NSO Cells
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C Detailed storage instructions below.

Description
Background:
E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells.1 E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone ａnd inflamed tissues.2 E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, ａnd delayed- type hypersensitivity, in arthritic joints, ａnd in heart ａnd renal allografts undergoing rejection.3 E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.4

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Rat E-Selectin is Mr 78 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110-120 kDa.
State of Matter
Lyophilized
Purity
>90% by SDS-PAGE ａnd analyzed by silver stain.
Storage ａnd Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
ynasselmty deasaycqrd ythlvaiqnk eeinylnstl ryspsyywig irkvnnvwiw vgtqkpltee aknwapgepn nkqrnedcve iyiqrpkdsg mwndercdkk klalcytasc tntscsghge cvetinsytc kchpgflgpk cdqvvtcqeq eypdhgslnc thpfglfsyn sscsfscerg yvpssmettv rctssgewsa papachvvec kaltqpahgv rkcssnpgsy pwnttctfdc eegyrrvgaq nlqctssgvw dnekpsckav tcdaiprpqn gsvscsnsta galafksscn ftcehsftlq gpaqvecsaq gqwtpqipvc kasqcealsa pqrghmkclp sasapfqsgs sckfscdegf elkgsrrlqc gprgewdsek ptcagvqcss ldlpgkmnms csgpavfgtv ceftcpegwt lngssiltcg atgrwsamlp tceapanppr pkscdkthtc ppcpapellg gpsvflfppk pkdtlmisrt pevtcvvvdv shedpevkfn wyvdgvevhn aktkpreeqy nstyrvvsvl tvlhqdwlng keykckvsnk alpapiekti skakgqprep qvytlppsrd eltknqvslt clvkgfypsd iavewesngq pennykttpp vldsdgsffl yskltvdksr wqqgnvfscs vmhealhnhy tqkslslspg k

Country of Origin
USA
References
1. Milstone D et al. （2004） PNAS 101: 8005
2. Dimitroff CJ et al. （2009） J Visualized Experiments
3. Takako Hirata et al. （2005） J Immunol. 175: 8042
4. Ramakrishnan Vanitha et al. （2003） Cancer Res. 63: 6387
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