产品编号:C1318-1

产品描述:Recombinant Human CD23 (Soluble)

反应种属:

实验方法:

标记:

规格:1mg

供应商:Leinco

价格(RMB):面议

订购:

说明书:

Recombinant Human Cluster Of Differentiation 23
Purified No Carrier Protein
（FCER2, CD23A, CLEC4J, FCE2, IGEBF, OKT10, Leu20, B6, or Blast-2, 18.6 Antigen）
Prod. No.: C1318
Source E. coli
Pkg. Size: 1 mg, 20 µg
Storage: -20°C to -70°C Detailed storage instructions below.

Description
Background:
CD23 （cluster of differentiation 23）, also known as Fc epsilon RII or FcεRII, is a type 2 transmembrane C-type lectin ａnd a member of the Ig family that is expressed on most mature B cells. CD23 is a surface marker of activated B cells as well as a low-affinity Fc receptor for IgE.1 CD23 has pleiotropic roles in the control of lymphocyte behaviour, suggesting that CD23 may interact with another ligand in addition to IgE.2 CD23 is important in the differentiation of chronic lymphocytic leukemia （CLL） from other lymphoid leukemias.3

Source
E. coli
Molecular Weight
The molecular weight of Recombinant Human sCD23 is Mr 19.2 kDa.
State of Matter
Lyophilized
Purity
>95% by SDS-PAGE ａnd HPLC
Storage ａnd Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<0.1 EU/µg as determined by the LAL method
Amino Acid Sequence
MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS

Country of Origin
USA
References
1. Sakai H et al. （1992） Nephron 60: 404
2. Jean-Yves et al. （1992） Nature 358: 505
3. Micheal Keating et al. （2002） Cancer 94: 1721

Related Products
Recombinant Human CD23 （Leinco Prod. No.: C1591）