产品编号:I-305
产品描述:Anti-Human IL-1RAcP(CT-1)
反应种属:
实验方法:
标记:
规格:0.5mg
供应商:Leinco
价格(RMB):16095.00
订购:
说明书:
Rabbit Anti-Human Interleukin-1 Receptor Accessory Protein (IL-1RAcP)
Purified No Carrier Protein
(IL1RAP)
Polyclonal Antibody
Prod. No.: I-305
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human IL-1 Receptor Accessory Protein (IL-1RAcP) recognizes an epitope near the C-terminus of Human IL-1RAcP. This polyclonal antibody was purified using affinity chromatography.
Background:
IL-1R accessory protein (IL-1RAcP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. IL-1RAcP is an indispensible molecule in the IL-1 receptor signal transduction complex, necessary to link events on the plasma membrane level to downstream signaling pathways, allowing IL-1-dependent activation of transcription factors and gene expression.1 IL-1R AcP represents a novel target for blocking IL-1 function in human disease.2
Known Species Cross Reactivity: Hu+
Immunogen
IL-1RAcP (CT-1) Blocking Peptide (Leinco Prod. No.: I-320)
Blocking Peptide
IL-1RAcP (CT-1) Blocking Peptide (Leinco Prod. No.: I-320)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
References
1. Martin MU et al. (1997) J Biol Chem. 272: 7727
2. Labow MA et al. (1998) J Immunol. 161: 5614
Related Products
IL-1RAcP (CT-1) Blocking Peptide (Leinco Prod. No.: I-320)
IL-1RAcP (CT-2) Blocking Peptide (Leinco Prod. No.: I-319)
Anti-Human IL-1RAcP (CT-2) (Leinco Prod. No.: I-306)
IL-1RAcP (CT-1) Blocking Peptide (Leinco Prod. No.: I-476)
IL-1RAcP (CT-2) Blocking Peptide (Leinco Prod. No.: I-477)
Recombinant Human IL-1 RAcP (Leinco Prod. No.: I-578)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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