产品编号:N149
产品描述:Anti-Human NGFR
反应种属:
实验方法:
标记:
规格:0.5mg
供应商:Leinco
价格(RMB):16095.00
订购:
说明书:
Rabbit Anti-Human Nerve Growth Factor Receptor (NGFR)
Purified No Carrier Protein
(CD271, TNFRSF16, P75 (Neurotrophin Receptor) NTR, LNGFR)
Polyclonal Antibody
Prod. No.: N149
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human Nerve Growth Factor Receptor (NGFR) recognizes Human NGFR. This polyclonal antibody was purified using affinity chromatography.
Background:
Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.1 It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.2 p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.3
Known Species Cross Reactivity: Ms+, Hu+
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), IHC (Frozen), WB
References
1. Ashworth A. et al. (2006) Modern Path. 19: 307
2. Carter BD et al. (2004) Prog. Brain Res. 146: 25
3. Itano T. et al. (2001) Acta Med Okayama 55: 19
Related Products
Recombinant Human NGF R (Leinco Prod. No.: N187)
Anti-Human NGF R (Antigen Aff. Pur.) (Leinco Prod. No.: N194)
Recombinant Mouse NGF R (Leinco Prod. No.: N183)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
