产品编号:T295
产品描述:Anti-Human TTC5
反应种属:
实验方法:
标记:
规格:0.5mg
供应商:Leinco
价格(RMB):17925.00
订购:
说明书:
Rabbit Anti-Human Tetratricopeptide Repeat Protein 5 (TTC5)
Purified No Carrier Protein
(TPR Repeat Protein 5)
Polyclonal Antibody
Prod. No.: T295
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human Tetratricopeptide Repeat Protein 5 (TTC5) recognizes Human and Mouse TTC5. This polyclonal antibody was purified using affinity chromatography.
Background:
Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats.1 Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90,2 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5,3 suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Known Species Cross Reactivity: Ms+, Hu+
Immunogen
Tetratricopeptide Repeat Protein 5 Blocking Peptide (Leinco Prod. No.: T302)
Blocking Peptide
Tetratricopeptide Repeat Protein 5 Blocking Peptide (Leinco Prod. No.: T302)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
Western Blotting: This antibody can be used to detect Human and Mouse TTC5 by Western blot analysis at a concentration of 0.5-1.0 µg/ml when used in conjunction with compatible secondary reagents, such as Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190), under either reducing or non-reducing conditions. The positive control for Western blotting is RAW 264.7 Whole Cell Lysate (Leinco Prod. No.: R1174)
References
1. Blatch, G. L. et al. (1999) BioEssays 21:932
2. Song, Y. et al. (2005) J. Biol. Chem. 280:34178
3. Yang, J. et al. (2005) EMBO J. 24:1
Related Products
Tetratricopeptide Repeat Protein 5 Blocking Peptide (Leinco Prod. No.: T302)
Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190)
RAW 264.7 Whole Cell Lysate (Leinco Prod. No.: R1174)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
