产品编号:I-500
产品描述:Anti-Human IL-27
反应种属:
实验方法:
标记:
规格:0.5mg
供应商:Leinco
价格(RMB):17925.00
订购:
说明书:
Rabbit Anti-Human Interleukin-27 (IL-27)
Purified No Carrier Protein
(P28, IL30, IL-27, IL-27p28, IL27)
Polyclonal Antibody
Prod. No.: I-500
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human Interleukin-27 (IL-27) recognizes an epitope in the intermediate domain of Human and Mouse IL-27. This polyclonal antibody was purified using affinity chromatography.
Background:
Interleukin-27 (IL-27) is a novel IL-12 family member that plays a role in the early regulation of T helper cell 1 initiation, including induction of T-bet and IL-12 receptor beta 2 expression.1 IL-27 is produced by antigen-presenting cells2 and plays an important function in regulating the activity of B and T lymphocytes.3 IL27 may be a potential therapeutic agent against rheumatoid arthritis (RA) at the onset of the disease.4
Known Species Cross Reactivity: Ms+, Hu+
Immunogen
IL-27 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: I-512)
Blocking Peptide
IL-27 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: I-512)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
WB
References
1. Yoshimoto T et al. (2004) Cancer Res. 64: 1152
2. De Sauvage FJ et al. (2003) Proceedings of the National Acad of Sci of USA 100: 15047
3. Devergne O et al. (2006) J Immunol. 176: 5890
4. Liew FY et al. (2008) Ann Rheum Dis. 67: 1474
Related Products
IL-27 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: I-512)
Anti-Human IL-27 (NT) (Leinco Prod. No.: I-501)
IL-27 (NT) Blocking Peptide (Leinco Prod. No.: I-513)
Recombinant Mouse IL-27 (p28) (Leinco Prod. No.: I-811)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
