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Plasminogen Activator Inhibitor 1

产品编号:RCP9092

产品描述:Plasminogen Activator Inhibitor 1

反应种属:

实验方法:

标记:

规格:100µg

供应商:Randox

价格(RMB):6400.00

订购:订购

说明书:

Description: PAI-1 is a serine protease inhibitor, which can exist either in an active inhibitory conformation or in an inactive or latent conformation. PAI-1 is produced mainly by the endothelium but is also secreted by other tissue types including adipose tissue. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, therefore inhibiting fibrinolysis. Increased levels of PAI-1 have been linked with various conditions including cardiovascular disease, thrombosis, insulin resistance and obesity. RANDOX recombinant PAI-1 comprises a 379 amino acid fragment (24-402) corresponding to the mature PAI-1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Form: Liquid
Purity: >95% by SDS-PAGE
References: Gils, A & Declerck, P.J. 2004 Curr. Med. Chem. 11 (17) : 2323- 2334.